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1,3-Diamine-Derived Catalysts: Design, Synthesis, and the Use in Enantioselective Mannich Reactions of Ketones

[Image: see text] 1,3-Diamine-derived catalysts were designed, synthesized, and used in asymmetric Mannich reactions of ketones. The reactions catalyzed by one of the 1,3-diamine derivatives in the presence of acids afforded the Mannich products with high enantioselectivities under mild conditions....

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Detalles Bibliográficos
Autores principales: Garg, Yuvraj, Osborne, James, Vasylevskyi, Serhii, Velmurugan, Nivedha, Tanaka, Fujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407930/
https://www.ncbi.nlm.nih.gov/pubmed/37460110
http://dx.doi.org/10.1021/acs.joc.3c01051

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