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Potential of Negative-Ion-Mode Proteomics: An MS1-Only Approach

[Image: see text] Current proteomics approaches rely almost exclusively on using the positive ionization mode, resulting in inefficient ionization of many acidic peptides. This study investigates protein identification efficiency in the negative ionization mode using the DirectMS1 method. DirectMS1...

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Detalles Bibliográficos
Autores principales:	Penanes, Pelayo A., Gorshkov, Vladimir, Ivanov, Mark V., Gorshkov, Mikhail V., Kjeldsen, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407931/ https://www.ncbi.nlm.nih.gov/pubmed/37395192 http://dx.doi.org/10.1021/acs.jproteome.3c00307

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