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Chemoenzymatic Synthesis of Tenofovir
[Image: see text] We report on novel chemoenzymatic routes toward tenofovir using low-cost starting materials and commercial or homemade enzyme preparations as biocatalysts. The biocatalytic key step was accomplished either via stereoselective reduction using an alcohol dehydrogenase or via kinetic...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407936/ https://www.ncbi.nlm.nih.gov/pubmed/37467462 http://dx.doi.org/10.1021/acs.joc.3c01005 |