Cargando…

1,25(OH)(2)D(3) ameliorates doxorubicin‑induced cardiomyopathy by inhibiting the NLRP3 inflammasome and oxidative stress

Doxorubicin (DOX), as a chemotherapy agent with marked therapeutic effect, can be used to treat certain types of cancer such as leukemia, lymphoma and breast cancer. However, the toxic effects of DOX on cardiomyocytes limit its clinical application. Oxidative stress has been documented to serve a pi...

Descripción completa

Detalles Bibliográficos
Autores principales: Gu, Xin, Zhao, Lin, Ye, Jiabao, Chen, Lin, Sui, Chenyan, Li, Baihong, Wang, Xiaoyan, Zhang, Jun, Du, Yingqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407981/
https://www.ncbi.nlm.nih.gov/pubmed/37559932
http://dx.doi.org/10.3892/etm.2023.12112