GATA2 co-opts TGFβ1/SMAD4 oncogenic signaling and inherited variants at 6q22 to modulate prostate cancer progression

BACKGROUND: Aberrant somatic genomic alteration including copy number amplification is a hallmark of cancer genomes. We previously profiled genomic landscapes of prostate cancer (PCa), yet the underlying causal genes with prognostic potential has not been defined. It remains unclear how a somatic ge...

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Detalles Bibliográficos
Autores principales: Yang, Xiayun, Zhang, Qin, Li, Shuxuan, Devarajan, Raman, Luo, Binjie, Tan, Zenglai, Wang, Zixian, Giannareas, Nikolaos, Wenta, Tomasz, Ma, Wenlong, Li, Yuqing, Yang, Yuehong, Manninen, Aki, Wu, Song, Wei, Gong-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10408074/
https://www.ncbi.nlm.nih.gov/pubmed/37550764
http://dx.doi.org/10.1186/s13046-023-02745-7

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