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Global effects of identity and aging on the human sperm methylome

BACKGROUND: As the average age of fatherhood increases worldwide, so too does the need for understanding effects of aging in male germline cells. Molecular change, including epigenomic alterations, may impact offspring. Age-associated change to DNA cytosine methylation in the cytosine–guanine (CpG)...

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Detalles Bibliográficos
Autores principales: de Sena Brandine, Guilherme, Aston, Kenneth I., Jenkins, Timothy G., Smith, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10408082/
https://www.ncbi.nlm.nih.gov/pubmed/37550724
http://dx.doi.org/10.1186/s13148-023-01541-6