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Transcriptomic comparison of bone marrow CD34 + cells and peripheral blood neutrophils from ET patients with JAK2 or CALR mutations

BACKGROUND: Essential thrombocythemia (ET) is one of the most common types of Ph-negative myeloproliferative neoplasms, an infrequent group of blood cancers that arise from a CD34 + hematopoietic stem cell (HSC) in the bone marrow (BM) primarily due to driver mutations in JAK2, CALR or MPL. These ab...

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Detalles Bibliográficos
Autores principales: Guijarro-Hernández, Ana, Vizmanos, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10408115/
https://www.ncbi.nlm.nih.gov/pubmed/37550636
http://dx.doi.org/10.1186/s12863-023-01142-5