The G285S mutation in nsP1 is sufficient to render Sindbis virus as a stable vector for gene delivery

Neuroscience, gene therapy, and vaccine have all benefited from the increased use of viral vectors. Sindbis virus (SINV) is a notable candidate among these vectors. However, viral vectors commonly suffer from a loss of expression of the transgene, especially RNA viral vectors. In this study, we used...

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Detalles Bibliográficos
Autores principales: Shi, Xiangwei, Sun, Kangyixin, Hu, You, Wang, Qinghan, Liao, Guoyang, Li, Li, Wen, Pengjie, Wong, Leo E., Jia, Fan, Xu, Fuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10408454/
https://www.ncbi.nlm.nih.gov/pubmed/37560523
http://dx.doi.org/10.3389/fmicb.2023.1229506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10408454/
https://www.ncbi.nlm.nih.gov/pubmed/37560523
http://dx.doi.org/10.3389/fmicb.2023.1229506

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