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The G285S mutation in nsP1 is sufficient to render Sindbis virus as a stable vector for gene delivery
Neuroscience, gene therapy, and vaccine have all benefited from the increased use of viral vectors. Sindbis virus (SINV) is a notable candidate among these vectors. However, viral vectors commonly suffer from a loss of expression of the transgene, especially RNA viral vectors. In this study, we used...
Autores principales: | Shi, Xiangwei, Sun, Kangyixin, Hu, You, Wang, Qinghan, Liao, Guoyang, Li, Li, Wen, Pengjie, Wong, Leo E., Jia, Fan, Xu, Fuqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10408454/ https://www.ncbi.nlm.nih.gov/pubmed/37560523 http://dx.doi.org/10.3389/fmicb.2023.1229506 |
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