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An independent evaluation in a CRC patient cohort of microbiome 16S rRNA sequence analysis methods: OTU clustering, DADA2, and Deblur

16S rRNA is the universal gene of microbes, and it is often used as a target gene to obtain profiles of microbial communities via next-generation sequencing (NGS) technology. Traditionally, sequences are clustered into operational taxonomic units (OTUs) at a 97% threshold based on the taxonomic stan...

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Detalles Bibliográficos
Autores principales: Liu, Guang, Li, Tong, Zhu, Xiaoyan, Zhang, Xuanping, Wang, Jiayin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10408458/
https://www.ncbi.nlm.nih.gov/pubmed/37560524
http://dx.doi.org/10.3389/fmicb.2023.1178744