Synthesis, Biological Evaluation and Molecular Docking Studies of Novel Series of Bis-1,2,4-Triazoles as Thymidine Phosphorylase Inhibitor

INTRODUCTION: Heterocyclic compounds have diverse biological activities and potential in drug development. This study aims to synthesize novel compounds with two 1,2,4-triazole cores and evaluate their biological properties, particularly their inhibitory activity against thymidine phosphorylase (TP)...

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Detalles Bibliográficos
Autores principales: Korol, Nataliya, Holovko-Kamoshenkova, Oksana M, Slivka, Mikhailo, Pallah, Oleksandra, Onysko, Mykhailo Yu, Kryvovyaz, Andriy, Boyko, Nadiya V, Yaremko, Olha V, Mariychuk, Ruslan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10408706/
https://www.ncbi.nlm.nih.gov/pubmed/37560149
http://dx.doi.org/10.2147/AABC.S415961

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