Genome-wide CRISPR screen identifies genes synthetically lethal with GRA17, a nutrient channel encoding gene in Toxoplasma

Toxoplasma gondii is a parasite that replicates within a specialized compartment called the parasitophorous vacuole (PV), which is surrounded by the PV membrane (PVM). To obtain essential nutrients, Toxoplasma must transport molecules across the PVM, a process mediated by the secreted parasite prote...

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Detalles Bibliográficos
Autores principales: Paredes-Santos, Tatiana C., Bitew, Mebratu A., Swale, Christopher, Rodriguez, Felipe, Krishnamurthy, Shruthi, Wang, Yifan, Maru, Parag, Sangaré, Lamba Omar, Saeij, Jeroen P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409377/
https://www.ncbi.nlm.nih.gov/pubmed/37498952
http://dx.doi.org/10.1371/journal.ppat.1011543

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