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A mosaic adeno-associated virus vector as a versatile tool that exhibits high levels of transgene expression and neuron specificity in primate brain

Recent emphasis has been placed on gene transduction mediated through recombinant adeno-associated virus (AAV) vector to manipulate activity of neurons and their circuitry in the primate brain. In the present study, we created a novel vector of which capsid was composed of capsid proteins derived fr...

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Detalles Bibliográficos
Autores principales: Kimura, Kei, Nagai, Yuji, Hatanaka, Gaku, Fang, Yang, Tanabe, Soshi, Zheng, Andi, Fujiwara, Maki, Nakano, Mayuko, Hori, Yukiko, Takeuchi, Ryosuke F., Inagaki, Mikio, Minamimoto, Takafumi, Fujita, Ichiro, Inoue, Ken-ichi, Takada, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409865/
https://www.ncbi.nlm.nih.gov/pubmed/37553329
http://dx.doi.org/10.1038/s41467-023-40436-1