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脂质纳米粒递送靶向Cyp2e1基因的小干扰RNA可减轻小鼠亚急性酒精性肝损伤
OBJECTIVE: To investigate the effect and mechanism of lipid nanoparticle (LNP) delivery of small interfering RNA (siRNA) targeting Cyp2e1 gene on subacute alcoholic liver injury in mice. METHODS: siRNA targeting Cyp2e1 gene was encapsulated in LNP (si-Cyp2e1 LNP) by microfluidic technique and the re...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
《浙江大学学报》编辑部
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409911/ https://www.ncbi.nlm.nih.gov/pubmed/37476942 http://dx.doi.org/10.3724/zdxbyxb-2022-0729 |