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The growth hormone receptor interacts with transcriptional regulator HMGN1 upon GH-induced nuclear translocation

ABSTRACT: Growth hormone (GH) actions are mediated through binding to its cell-surface receptor, the GH receptor (GHR), with consequent activation of downstream signalling. However, nuclear GHR localisation has also been observed and is associated with increased cancer cell proliferation. Here we in...

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Detalles Bibliográficos
Autores principales: Jain, Lekha, Vickers, Mark H., Jacob, Bincy, Middleditch, Martin J., Chudakova, Daria A., Ganley, Austen R. D., O’Sullivan, Justin M., Perry, Jo K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409943/
https://www.ncbi.nlm.nih.gov/pubmed/37043098
http://dx.doi.org/10.1007/s12079-023-00741-2