Young donor hematopoietic stem cells revitalize aged or damaged bone marrow niche by transdifferentiating into functional niche cells

The bone marrow niche maintains hematopoietic stem cell (HSC) homeostasis and declines in function in the physiologically aging population and in patients with hematological malignancies. A fundamental question is now whether and how HSCs are able to renew or repair their niche. Here, we show that d...

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Detalles Bibliográficos
Autores principales: Yuan, Na, Wei, Wen, Ji, Li, Qian, Jiawei, Jin, Zhicong, Liu, Hong, Xu, Li, Li, Lei, Zhao, Chen, Gao, Xueqin, He, Yulong, Wang, Mingyuan, Tang, Longhai, Fang, Yixuan, Wang, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410009/
https://www.ncbi.nlm.nih.gov/pubmed/37226323
http://dx.doi.org/10.1111/acel.13889

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