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Unbiased evaluation of rapamycin's specificity as an mTOR inhibitor
Rapamycin is a macrolide antibiotic that functions as an immunosuppressive and anti‐cancer agent, and displays robust anti‐ageing effects in multiple organisms including humans. Importantly, rapamycin analogues (rapalogs) are of clinical importance against certain cancer types and neurodevelopmental...
Autores principales: | Artoni, Filippo, Grützmacher, Nina, Demetriades, Constantinos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410055/ https://www.ncbi.nlm.nih.gov/pubmed/37222020 http://dx.doi.org/10.1111/acel.13888 |
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