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IKBKB reduces huntingtin aggregation by phosphorylating serine 13 via a non-canonical IKK pathway

N-terminal phosphorylation at residues T3 and S13 is believed to have important beneficial implications for the biological and pathological properties of mutant huntingtin, where inhibitor of nuclear factor kappa B kinase subunit beta (IKBKB) was identified as a candidate regulator of huntingtin N-t...

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Detalles Bibliográficos
Autores principales:	Cariulo, Cristina, Martufi, Paola, Verani, Margherita, Toledo-Sherman, Leticia, Lee, Ramee, Dominguez, Celia, Petricca, Lara, Caricasole, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410066/ https://www.ncbi.nlm.nih.gov/pubmed/37553253 http://dx.doi.org/10.26508/lsa.202302006

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