WBP2 restrains the lysosomal degradation of GPX4 to inhibit ferroptosis in cisplatin-induced acute kidney injury

Cisplatin is one of the major causes of acute kidney injury (AKI) in clinical practice, and ferroptosis is an essential form of cell death in cisplatin-induced AKI (CP-AKI). WW domain binding protein-2 (WBP2), a molecular chaperon, is involved in the progression of various malignancies, but its role...

Descripción completa

Detalles Bibliográficos
Autores principales: Deng, Zebin, Wang, Yilong, Liu, Jiachen, Zhang, Hao, Zhou, Lizhi, Zhao, Hao, Han, Yachun, Yan, Shu, Dong, Zheng, Wang, Yinhuai, Dai, Yingbo, Deng, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410181/
https://www.ncbi.nlm.nih.gov/pubmed/37516014
http://dx.doi.org/10.1016/j.redox.2023.102826

Ejemplares similares

Ejemplares similares