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Establishment of a mathematical prediction model for voriconazole stable maintenance dose: a prospective study

BACKGROUND: In patients with invasive fungal infection (IFI), the steady-state serum trough concentration (C (min)) of voriconazole (VCZ) is highly variable and can lead to treatment failure (C (min) < 0.5 mg/L) and toxicity (C (min) ≥ 5.0 mg/L). However, It remains challenging to determine the i...

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Detalles Bibliográficos
Autores principales: Zhou, Lijuan, Li, Min, Li, Huihong, Guo, Zhiqiang, Gao, Yanqiu, Zhang, Hua, Qin, Fuli, Sang, Zhihui, Xing, Qinghe, Cheng, Long, Cao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410275/
https://www.ncbi.nlm.nih.gov/pubmed/37565064
http://dx.doi.org/10.3389/fcimb.2023.1157944