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p53 promotes the expansion of regulatory T cells via DNMT3a- and TET2- mediated Foxp3 expression in sepsis

BACKGROUND: Immunosuppression is an important characteristic of sepsis and is closely related to poor outcomes. Regulatory T cells (Tregs) contribute to immune suppression by inhibiting effector T cell (Teff) proliferation and differentiation. We aimed to investigate the role of p53 in Treg expansio...

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Detalles Bibliográficos
Autores principales:	Zhang, Hui, Wu, Tiantian, Ren, Chao, Dong, Ning, Wu, Yao, Yao, Yongming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410290/ https://www.ncbi.nlm.nih.gov/pubmed/37564681 http://dx.doi.org/10.1093/burnst/tkad021

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