Cargando…
Specific attributes of the V(L) domain influence both the structure and structural variability of CDR-H3 through steric effects
Antibodies, through their ability to target virtually any epitope, play a key role in driving the adaptive immune response in jawed vertebrates. The binding domains of standard antibodies are their variable light (V(L)) and heavy (V(H)) domains, both of which present analogous complementarity-determ...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410447/ https://www.ncbi.nlm.nih.gov/pubmed/37564639 http://dx.doi.org/10.3389/fimmu.2023.1223802 |