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Chromatin conformational changes at human satellite II contribute to the senescence phenotype in the tumor microenvironment
Cellular senescence and senescence-associated secretory phenotype (SASP) in stromal cells within the tumor microenvironment promote cancer progression. Although cellular senescence has been shown to induce changes in the higher-order chromatin structure and abnormal transcription of repetitive eleme...
Autores principales: | Miyata, Kenichi, Zhou, Xiangyu, Nishio, Mika, Hanyu, Aki, Chiba, Masatomo, Kawasaki, Hiroko, Osako, Tomo, Takeuchi, Kengo, Ohno, Shinji, Ueno, Takayuki, Maruyama, Reo, Takahashi, Akiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410700/ https://www.ncbi.nlm.nih.gov/pubmed/37523559 http://dx.doi.org/10.1073/pnas.2305046120 |
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