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Mitochondrial sulfide promotes life span and health span through distinct mechanisms in developing versus adult treated Caenorhabditis elegans

Living longer without simultaneously extending years spent in good health (“health span”) is an increasing societal burden, demanding new therapeutic strategies. Hydrogen sulfide (H(2)S) can correct disease-related mitochondrial metabolic deficiencies, and supraphysiological H(2)S concentrations can...

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Detalles Bibliográficos
Autores principales: Vintila, Adriana Raluca, Slade, Luke, Cooke, Michael, Willis, Craig R. G., Torregrossa, Roberta, Rahman, Mizanur, Anupom, Taslim, Vanapalli, Siva A., Gaffney, Christopher J., Gharahdaghi, Nima, Szabo, Csaba, Szewczyk, Nathaniel J., Whiteman, Matthew, Etheridge, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410709/
https://www.ncbi.nlm.nih.gov/pubmed/37523525
http://dx.doi.org/10.1073/pnas.2216141120