Non-inferiority trial of a shorter (7 days) compared with a longer (14 days) duration of antimicrobial therapy for the treatment of bacteraemic urinary sepsis, measured by microbiological success after the completion of therapy: a substudy protocol for the Bacteraemia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE) multicentre randomised controlled trial

INTRODUCTION: The BALANCE study is a randomised clinical trial (3626 participants) designed to assess the non-inferiority of 7 days (short-course) antibiotic therapy compared with 14 days of therapy for bacteraemia using the pragmatic endpoint of 90-day survival. Based on pilot study data, approxima...

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Detalles Bibliográficos
Autores principales: Rogers, Benjamin A, Fowler, Robert, Harris, Patrick N A, Davis, Joshua S, Pinto, Ruxandra L, Bhatia Dwivedi, Dhiraj, Rishu, Asgar, Shehabi, Yahya, Daneman, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Infectious Diseases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410794/
https://www.ncbi.nlm.nih.gov/pubmed/37369422
http://dx.doi.org/10.1136/bmjopen-2022-069708

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