Identification of GRIN2D as a novel therapeutic target in pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with a dismal prognosis, and despite significant advances in our understanding of its genetic drivers, like KRAS, TP53, CDKN2A, and SMAD4, effective therapies remain limited. Here, we identified a new therapeutic target GRI...

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Detalles Bibliográficos
Autores principales: Wang, Jiatong, Wong, Chi Hin, Zhu, Yinxin, Yao, Xiaoqiang, Ng, Kelvin K C, Zhou, Chengzhi, To, Ka Fai, Chen, Yangchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410818/
https://www.ncbi.nlm.nih.gov/pubmed/37553583
http://dx.doi.org/10.1186/s40364-023-00514-4

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