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G-MDSC-derived exosomes mediate the differentiation of M-MDSC into M2 macrophages promoting colitis-to-cancer transition

BACKGROUNDS: In inflammatory bowel disease microenvironment, transdifferentiation of myeloid-derived suppressor cells (MDSCs) and M2 macrophage accumulation are crucial for the transition of colitis-to-cancer. New insights into the cross-talk and the underling mechanism between MDSCs and M2 macropha...

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Detalles Bibliográficos
Autores principales: Wang, Yungang, Liu, Hongli, Zhang, Zhe, Bian, Dezhi, Shao, Keke, Wang, Shengjun, Ding, Yanxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410840/
https://www.ncbi.nlm.nih.gov/pubmed/37364932
http://dx.doi.org/10.1136/jitc-2022-006166