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The roles of METTL3 on autophagy and proliferation of vascular smooth muscle cells are mediated by mTOR rather than by CDK1

BACKGROUND: Aberrant proliferation of vascular smooth muscle cells (VSMCs) is the cause of neointima formation followed by vascular injury. Autophagy is involved in this pathological process, but its function is controversial. Recently, we found that methyltransferase like 3 (METTL3) inhibited VSMC...

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Detalles Bibliográficos
Autores principales: Luo, Hanshen, Wu, Xingliang, Huo, Bo, Liu, Liyuan, Jiang, Ding-Sheng, Yi, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411010/
https://www.ncbi.nlm.nih.gov/pubmed/37559091
http://dx.doi.org/10.1186/s13008-023-00096-5