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The roles of METTL3 on autophagy and proliferation of vascular smooth muscle cells are mediated by mTOR rather than by CDK1
BACKGROUND: Aberrant proliferation of vascular smooth muscle cells (VSMCs) is the cause of neointima formation followed by vascular injury. Autophagy is involved in this pathological process, but its function is controversial. Recently, we found that methyltransferase like 3 (METTL3) inhibited VSMC...
Autores principales: | Luo, Hanshen, Wu, Xingliang, Huo, Bo, Liu, Liyuan, Jiang, Ding-Sheng, Yi, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411010/ https://www.ncbi.nlm.nih.gov/pubmed/37559091 http://dx.doi.org/10.1186/s13008-023-00096-5 |
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