Macrophage-organoid co-culture model for identifying treatment strategies against macrophage-related gemcitabine resistance

BACKGROUND: Gemcitabine resistance (GR) is a significant clinical challenge in pancreatic adenocarcinoma (PAAD) treatment. Macrophages in the tumor immune-microenvironment are closely related to GR. Uncovering the macrophage-induced GR mechanism could help devise a novel strategy to improve gemcitab...

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Detalles Bibliográficos
Autores principales: Jiang, Shengwei, Deng, Tingwei, Cheng, Huan, Liu, Weihan, Shi, Dan, Yuan, Jiahui, He, Zhiwei, Wang, Weiwei, Chen, Boning, Ma, Li, Zhang, Xianbin, Gong, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411021/
https://www.ncbi.nlm.nih.gov/pubmed/37553567
http://dx.doi.org/10.1186/s13046-023-02756-4

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