Gastric Metastasis of Primary Neuroendocrine Tumor of Skin: Rare Tumor with Rare Presentation

Merkel cell carcinoma (MCC) is a rare primary neuroendocrine tumor of the skin. It has an aggressive biological behavior and shows early local and distant metastasis. Diagnosis of MCC is a challenge and requires confirmation by immunohistochemistry (IHC). However, metastasis of MCC to the stomach is...

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Autores principales: Osama, Md Ali, Rao, Seema, Mittal, Tarun, Kumar, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411111/
https://www.ncbi.nlm.nih.gov/pubmed/37564238
http://dx.doi.org/10.1055/s-0042-1760670
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author Osama, Md Ali
Rao, Seema
Mittal, Tarun
Kumar, Sandeep
author_facet Osama, Md Ali
Rao, Seema
Mittal, Tarun
Kumar, Sandeep
author_sort Osama, Md Ali
collection PubMed
description Merkel cell carcinoma (MCC) is a rare primary neuroendocrine tumor of the skin. It has an aggressive biological behavior and shows early local and distant metastasis. Diagnosis of MCC is a challenge and requires confirmation by immunohistochemistry (IHC). However, metastasis of MCC to the stomach is extremely uncommon and is rarely reported in the literature. We hereby describe a patient with gastric metastasis of MCC, who presented with black tarry stool and was finally diagnosed on the basis of clinical history, histology, and IHC.
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spelling pubmed-104111112023-08-10 Gastric Metastasis of Primary Neuroendocrine Tumor of Skin: Rare Tumor with Rare Presentation Osama, Md Ali Rao, Seema Mittal, Tarun Kumar, Sandeep J Lab Physicians Merkel cell carcinoma (MCC) is a rare primary neuroendocrine tumor of the skin. It has an aggressive biological behavior and shows early local and distant metastasis. Diagnosis of MCC is a challenge and requires confirmation by immunohistochemistry (IHC). However, metastasis of MCC to the stomach is extremely uncommon and is rarely reported in the literature. We hereby describe a patient with gastric metastasis of MCC, who presented with black tarry stool and was finally diagnosed on the basis of clinical history, histology, and IHC. Thieme Medical and Scientific Publishers Pvt. Ltd. 2023-01-18 /pmc/articles/PMC10411111/ /pubmed/37564238 http://dx.doi.org/10.1055/s-0042-1760670 Text en The Indian Association of Laboratory Physicians. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Osama, Md Ali
Rao, Seema
Mittal, Tarun
Kumar, Sandeep
Gastric Metastasis of Primary Neuroendocrine Tumor of Skin: Rare Tumor with Rare Presentation
title Gastric Metastasis of Primary Neuroendocrine Tumor of Skin: Rare Tumor with Rare Presentation
title_full Gastric Metastasis of Primary Neuroendocrine Tumor of Skin: Rare Tumor with Rare Presentation
title_fullStr Gastric Metastasis of Primary Neuroendocrine Tumor of Skin: Rare Tumor with Rare Presentation
title_full_unstemmed Gastric Metastasis of Primary Neuroendocrine Tumor of Skin: Rare Tumor with Rare Presentation
title_short Gastric Metastasis of Primary Neuroendocrine Tumor of Skin: Rare Tumor with Rare Presentation
title_sort gastric metastasis of primary neuroendocrine tumor of skin: rare tumor with rare presentation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411111/
https://www.ncbi.nlm.nih.gov/pubmed/37564238
http://dx.doi.org/10.1055/s-0042-1760670
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AT mittaltarun gastricmetastasisofprimaryneuroendocrinetumorofskinraretumorwithrarepresentation
AT kumarsandeep gastricmetastasisofprimaryneuroendocrinetumorofskinraretumorwithrarepresentation

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