A Rapid Method for Determination of Serum Methotrexate Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry and Its Application in Therapeutic Drug Monitoring

Objectives  Methotrexate (MTX) has anticancer therapeutic potential with multiple doses-related adverse effects and toxicities. Immunoassays for therapeutic monitoring of serum MTX have their own limitations. Liquid chromatography–tandem mass spectrometry (LC-MS/MS) is considered as the reference me...

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Detalles Bibliográficos
Autores principales: Tripathy, Naresh Kumar, Mishra, Shravan Kumar, Nathan, Gopi, Srivastava, Shreya, Gupta, Anshul, Lingaiah, Raghavendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411162/
https://www.ncbi.nlm.nih.gov/pubmed/37564228
http://dx.doi.org/10.1055/s-0042-1760668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411162/
https://www.ncbi.nlm.nih.gov/pubmed/37564228
http://dx.doi.org/10.1055/s-0042-1760668

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