Exosomal-miR-129-2-3p derived from Fusobacterium nucleatum-infected intestinal epithelial cells promotes experimental colitis through regulating TIMELESS-mediated cellular senescence pathway

Fusobacterium nucleatum (Fn) infection is known to exacerbate ulcerative colitis (UC). However, the link between Fn-infected intestinal epithelial cell (IEC)-derived exosomes (Fn-Exo) and UC progression has not been investigated. Differentially expressed miRNAs in Fn-Exo and non-infected IECs-derive...

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Detalles Bibliográficos
Autores principales: Wei, Shuchun, Wu, Xiaohan, Chen, Meilin, Xiang, Zixuan, Li, Xiangyun, Zhang, Jixiang, Dong, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411316/
https://www.ncbi.nlm.nih.gov/pubmed/37550944
http://dx.doi.org/10.1080/19490976.2023.2240035

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