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Melatonin Ameliorates Hepatic Ferroptosis in NAFLD by Inhibiting ER Stress via the MT2/cAMP/PKA/IRE1 Signaling Pathway

Ferroptosis, an iron-dependent cell death form, has recently been observed in the development of non-alcoholic fatty liver disease (NAFLD). Melatonin (Mel) shows potential benefits for preventing and treating liver diseases. Whether and how Mel ameliorates hepatic ferroptosis in NAFLD is not fully u...

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Detalles Bibliográficos
Autores principales: Guan, Qingyun, Wang, Zixu, Hu, Keyu, Cao, Jing, Dong, Yulan, Chen, Yaoxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411470/
https://www.ncbi.nlm.nih.gov/pubmed/37564204
http://dx.doi.org/10.7150/ijbs.85883

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