Fragment expansion with NUDELs – poised DNA-encoded libraries

Optimisation of the affinity of lead compounds is a critical challenge in the identification of drug candidates and chemical probes and is a process that takes many years. Fragment-based drug discovery has become established as one of the methods of choice for drug discovery starting with small, low...

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Detalles Bibliográficos
Autores principales: Salvini, Catherine L. A., Darlot, Benoit, Davison, Jack, Martin, Mathew P., Tudhope, Susan J., Turberville, Shannon, Kawamura, Akane, Noble, Martin E. M., Wedge, Stephen R., Crawford, James J., Waring, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411621/
https://www.ncbi.nlm.nih.gov/pubmed/37564419
http://dx.doi.org/10.1039/d3sc01171b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411621/
https://www.ncbi.nlm.nih.gov/pubmed/37564419
http://dx.doi.org/10.1039/d3sc01171b

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