Challenges in using transcriptome data to study the c-di-GMP signaling network in Pseudomonas aeruginosa clinical isolates

In the Pseudomonas aeruginosa type strain PA14, 40 genes are known to encode for diguanylate cyclases (DGCs) and/or phosphodiesterases (PDEs), which modulate the intracellular pool of the nucleotide second messenger c-di-GMP. While in general, high levels of c-di-GMP drive the switch from highly mot...

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Detalles Bibliográficos
Autores principales: Gür, Melisa, Erdmann, Jelena, Will, Anke, Liang, Ziwei, Andersen, Jens Bo, Tolker-Nielsen, Tim, Häussler, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411656/
https://www.ncbi.nlm.nih.gov/pubmed/37564278
http://dx.doi.org/10.1093/femsmc/xtad012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411656/
https://www.ncbi.nlm.nih.gov/pubmed/37564278
http://dx.doi.org/10.1093/femsmc/xtad012

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