FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair

Interstrand DNA cross-links (ICLs) represent complex lesions that compromise genomic stability. Several pathways have been involved in ICL repair, but the extent of factors involved in the resolution of ICL-induced DNA double-strand breaks (DSBs) remains poorly defined. Using CRISPR-based genomics,...

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Detalles Bibliográficos
Autores principales: Pinedo-Carpio, Edgar, Dessapt, Julien, Beneyton, Adèle, Sacre, Lauralicia, Bérubé, Marie-Anne, Villot, Romain, Lavoie, Elise G., Coulombe, Yan, Blondeau, Andréanne, Boulais, Jonathan, Malina, Abba, Luo, Vincent M., Lazaratos, Anna-Maria, Côté, Jean-François, Mallette, Frédérick A., Guarné, Alba, Masson, Jean-Yves, Fradet-Turcotte, Amélie, Orthwein, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411901/
https://www.ncbi.nlm.nih.gov/pubmed/37556550
http://dx.doi.org/10.1126/sciadv.adf4082

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