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demuxmix: demultiplexing oligonucleotide-barcoded single-cell RNA sequencing data with regression mixture models

MOTIVATION: Droplet-based single-cell RNA sequencing (scRNA-seq) is widely used in biomedical research for interrogating the transcriptomes of single cells on a large scale. Pooling and processing cells from different samples together can reduce costs and batch effects. To pool cells, they are often...

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Detalles Bibliográficos
Autor principal: Klein, Hans-Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412409/
https://www.ncbi.nlm.nih.gov/pubmed/37527018
http://dx.doi.org/10.1093/bioinformatics/btad481