Loss of TAZ after YAP deletion severely impairs foregut development and worsens cholestatic hepatocellular injury

We previously showed that loss of yes-associated protein 1 (YAP) in early liver development (YAP(KO)) leads to an Alagille syndrome-like phenotype, with failure of intrahepatic bile duct development, severe cholestasis, and chronic hepatocyte adaptations to reduce liver injury. TAZ, a paralog of YAP...

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Detalles Bibliográficos
Autores principales: Gabdulkhakova, Adelya, Krutsenko, Yekaterina, Zhu, Junjie, Liu, Silvia, Poddar, Minakshi, Singh, Sucha, Ma, Xiaochao, Nejak-Bowen, Kari, Monga, Satdarshan P.S., Molina, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412434/
https://www.ncbi.nlm.nih.gov/pubmed/37556373
http://dx.doi.org/10.1097/HC9.0000000000000220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412434/
https://www.ncbi.nlm.nih.gov/pubmed/37556373
http://dx.doi.org/10.1097/HC9.0000000000000220

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