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Loss of TAZ after YAP deletion severely impairs foregut development and worsens cholestatic hepatocellular injury
We previously showed that loss of yes-associated protein 1 (YAP) in early liver development (YAP(KO)) leads to an Alagille syndrome-like phenotype, with failure of intrahepatic bile duct development, severe cholestasis, and chronic hepatocyte adaptations to reduce liver injury. TAZ, a paralog of YAP...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Lippincott Williams & Wilkins
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412434/ https://www.ncbi.nlm.nih.gov/pubmed/37556373 http://dx.doi.org/10.1097/HC9.0000000000000220 |