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cGAS–STING drives ageing-related inflammation and neurodegeneration

Low-grade inflammation is a hallmark of old age and a central driver of ageing-associated impairment and disease(1). Multiple factors can contribute to ageing-associated inflammation(2); however, the molecular pathways that transduce aberrant inflammatory signalling and their impact in natural agein...

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Detalles Bibliográficos
Autores principales: Gulen, Muhammet F., Samson, Natasha, Keller, Alexander, Schwabenland, Marius, Liu, Chong, Glück, Selene, Thacker, Vivek V., Favre, Lucie, Mangeat, Bastien, Kroese, Lona J., Krimpenfort, Paul, Prinz, Marco, Ablasser, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412454/
https://www.ncbi.nlm.nih.gov/pubmed/37532932
http://dx.doi.org/10.1038/s41586-023-06373-1