The RIG-I agonist M8 triggers cell death and natural killer cell activation in human papillomavirus-associated cancer and potentiates cisplatin cytotoxicity

Although the activation of innate immunity to treat a wide variety of cancers is gaining increasing attention, it has been poorly investigated in human papillomavirus (HPV)-associated malignancies. Because these tumors harbor a severely impaired cGAS-STING axis, but they still retain a largely funct...

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Detalles Bibliográficos
Autores principales: Girone, Carlo, Calati, Federica, Lo Cigno, Irene, Salvi, Valentina, Tassinari, Valentina, Schioppa, Tiziana, Borgogna, Cinzia, Lospinoso Severini, Ludovica, Hiscott, John, Cerboni, Cristina, Soriani, Alessandra, Bosisio, Daniela, Gariglio, Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412503/
https://www.ncbi.nlm.nih.gov/pubmed/37356050
http://dx.doi.org/10.1007/s00262-023-03483-7

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