Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer

BACKGROUND: Genetically engineered mouse models (GEMMs) of cancer are powerful tools to study mechanisms of disease progression and therapy response, yet little is known about how these models respond to multimodality therapy used in patients. Radiation therapy (RT) is frequently used to treat local...

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Detalles Bibliográficos
Autores principales: Schmidt, Daniel R., Gramatikov, Iva Monique T., Sheen, Allison, Williams, Christopher L., Hurwitz, Martina, Dodge, Laura E., Holupka, Edward, Kiger, W. S., Cornwall-Brady, Milton R., Huang, Wei, Mak, Howard H., Cormier, Kathleen S, Condon, Charlene, Dane Wittrup, K., Yilmaz, Ömer H., Stevenson, Mary Ann, Down, Julian D., Floyd, Scott R., Roper, Jatin, Vander Heiden, Matthew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412558/
https://www.ncbi.nlm.nih.gov/pubmed/37558833
http://dx.doi.org/10.1038/s43856-023-00336-3

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