A machine learning approach for thermodynamic modeling of the statically measured solubility of nilotinib hydrochloride monohydrate (anti-cancer drug) in supercritical CO(2)

Nilotinib hydrochloride monohydrate (NHM) is an anti-cancer drug whose solubility was statically determined in supercritical carbon dioxide (SC-CO(2)) for the first time at various temperatures (308–338 K) and pressures (120–270 bar). The mole fraction of the drug dissolved in SC-CO(2) ranged from 0...

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Detalles Bibliográficos
Autores principales: Nateghi, Hassan, Sodeifian, Gholamhossein, Razmimanesh, Fariba, Mohebbi Najm Abad, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412577/
https://www.ncbi.nlm.nih.gov/pubmed/37558797
http://dx.doi.org/10.1038/s41598-023-40231-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412577/
https://www.ncbi.nlm.nih.gov/pubmed/37558797
http://dx.doi.org/10.1038/s41598-023-40231-4

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