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A machine learning approach for thermodynamic modeling of the statically measured solubility of nilotinib hydrochloride monohydrate (anti-cancer drug) in supercritical CO(2)
Nilotinib hydrochloride monohydrate (NHM) is an anti-cancer drug whose solubility was statically determined in supercritical carbon dioxide (SC-CO(2)) for the first time at various temperatures (308–338 K) and pressures (120–270 bar). The mole fraction of the drug dissolved in SC-CO(2) ranged from 0...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412577/ https://www.ncbi.nlm.nih.gov/pubmed/37558797 http://dx.doi.org/10.1038/s41598-023-40231-4 |