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Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system
Chemokine receptors constitute an important subfamily of G protein-coupled receptors (GPCRs), and they are critically involved in a broad range of immune response mechanisms. Ligand promiscuity among these receptors makes them an interesting target to explore multiple aspects of biased agonism. Here...
Autores principales: | Sarma, Parishmita, Carino, Carlo Marion C., Seetharama, Deeksha, Pandey, Shubhi, Dwivedi-Agnihotri, Hemlata, Rui, Xue, Cao, Yubo, Kawakami, Kouki, Kumari, Poonam, Chen, Yu-Chih, Luker, Kathryn E., Yadav, Prem N., Luker, Gary D., Laporte, Stéphane A., Chen, Xin, Inoue, Asuka, Shukla, Arun K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412580/ https://www.ncbi.nlm.nih.gov/pubmed/37558722 http://dx.doi.org/10.1038/s41467-023-40482-9 |
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