Human liver single nuclear RNA sequencing implicates BMPR2, GDF15, arginine, and estrogen in portopulmonary hypertension

Portopulmonary hypertension (PoPH) is a type of pulmonary vascular disease due to portal hypertension that exhibits high morbidity and mortality. The mechanisms driving disease are unknown, and transcriptional characteristics unique to the PoPH liver remain unexplored. Here, we apply single nuclear...

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Detalles Bibliográficos
Autores principales: Jose, Arun, Elwing, Jean M., Kawut, Steven M., Pauciulo, Michael W., Sherman, Kenneth E., Nichols, William C., Fallon, Michael B., McCormack, Francis X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412637/
https://www.ncbi.nlm.nih.gov/pubmed/37558836
http://dx.doi.org/10.1038/s42003-023-05193-3

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