PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6

Epigenetic modifications play important roles during the pathogenesis of multiple myeloma (MM). Herein, we found that protein arginine methyltransferase 1 (PRMT1) was highly expressed in MM patients, which was positively correlated with MM stages. High PRMT1 expression was correlated with adverse pr...

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Detalles Bibliográficos
Autores principales: Jia, Yachun, Yu, Xiao, Liu, Rui, Shi, Luyi, Jin, Hua, Yang, Dan, Zhang, Xiaofeng, Shen, Ying, Feng, Yuandong, Zhang, Peihua, Yang, Yi, Zhang, Linlin, Zhang, Pengyu, Li, Zongfang, He, Aili, Kong, Guangyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412649/
https://www.ncbi.nlm.nih.gov/pubmed/37558663
http://dx.doi.org/10.1038/s41419-023-06036-z

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