Cell-specific MAPT gene expression is preserved in neuronal and glial tau cytopathologies in progressive supranuclear palsy

Microtubule-associated protein tau (MAPT) aggregates in neurons, astrocytes and oligodendrocytes in a number of neurodegenerative diseases, including progressive supranuclear palsy (PSP). Tau is a target of therapy and the strategy includes either the elimination of pathological tau aggregates or re...

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Detalles Bibliográficos
Autores principales: Forrest, Shelley L., Lee, Seojin, Nassir, Nasna, Martinez-Valbuena, Ivan, Sackmann, Valerie, Li, Jun, Ahmed, Awab, Tartaglia, Maria Carmela, Ittner, Lars M., Lang, Anthony E., Uddin, Mohammed, Kovacs, Gabor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412651/
https://www.ncbi.nlm.nih.gov/pubmed/37354322
http://dx.doi.org/10.1007/s00401-023-02604-x

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