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IL-33 Downregulates Hepatic Carboxylesterase 1 in Acute Liver Injury via Macrophage-derived Exosomal miR-27b-3p

BACKGROUND AND AIMS: We previously reported that carboxylesterase 1 (CES1) expression was suppressed following liver injury. The study aimed to explore the role of interleukin (IL)-33 in liver injury and examine the mechanism by which IL-33 regulates CES1. METHODS: IL-33 and CES1 levels were determi...

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Detalles Bibliográficos
Autores principales: Gao, Ping, Li, Min, Lu, Jingli, Xiang, Daochun, Wang, Ximin, Xu, Yanjiao, Zu, Yue, Guan, Xinlei, Li, Guodong, Zhang, Chengliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412689/
https://www.ncbi.nlm.nih.gov/pubmed/37577217
http://dx.doi.org/10.14218/JCTH.2022.00144